All News

The paradigm for the medical management of benign prostatic hyperplasia has undergone a significant change during the past decade. Guided by new research, the approval of novel pharmaceutical and minimally invasive therapies, and the economics of health care financing, physicians have altered their approach to patient care in distinct ways.

Chicago-Resistance to drugs commonly used against uncomplicated urinary tract infections continues to grow, according to the results of a large North American study presented at the 43rd Interscience Conference on Antimicrobials and Chemotherapy.

Winston-Salem, NC--Some men may be more prone to prostate cancer because a variation in a specific gene makes them more susceptible to the harmful effects of cancer-causing agents, a new study shows.

Salt Lake City--Prostate cancer researchers say they have developed methods to predict treatment failure in men undergoing radiation therapy that is more precise and specific than current American Society for Therapeutic Radiology and Oncology guidelines.

Large-scale telephone-based management of eligible women with presumedcystitis is associated with low clinical recurrence rates and a very lowincidence of other gynecourologic diagnoses, according to a study by a largeHMO in California.

Scientists at Northwestern University have developed an ultra-sensitivetechnology based on gold nanoparticles and DNA that can detect PSA whenpresent at extremely low levels in the blood sample. The new protein-detectionmethod could be used to monitor prostate cancer patients following surgery,according to the researchers, whose findings are published in the Sept.26 issue of the journal Science (2003; 301:1884-6).

A 4-year screening interval was found adequate for detecting most cancersin a large European randomized trial of prostate cancer screening, accordingto a study in the Oct. 1 issue of the Journal of the National CancerInstitute (2003; 95:1462-6).

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Los Angeles-After a follow-up of almost 2 years, 70% of patients withstress urinary incontinence reported no repeat SUI after surgery with syntheticpolypropylene sling material, according to UCLA researchers.

Montreal, Quebec-The interval between transurethral resection of bladdertumor and radical cystectomy significantly influences 3-year disease recurrencerates in patients with transitional cell carcinoma of the bladder, saidresearchers from McGill University in Montreal.

Chicago-Neoadjuvant platinum-based chemotherapy is associatedwith a statistically significant improvement in the overall survival ofpatients with locally advanced bladder cancer, according to the resultsof a recent meta-analysis presented at the AUA annual meeting here. However,the treatment benefit is not strong enough to support a recommendation forusing neoadjuvant chemotherapy in this setting, said Amir Sherif, MD, PhD,speaking on behalf of the Nordic Cooperative Bladder Cancer Group.

Albuquerque, NM-A new outcome model of prostate cancer progression followingradical prostatectomy has demonstrated good correlation between the model'spredictions and actual patient data. A study using this model suggests thatmen benefit more from radical prostatectomy over watchful waiting, evenif residual disease remains after surgery.

New Products & Services

Once-daily quinolone gains new urology indications: West Haven, CT-Bayer Pharmaceuticals has received FDA approval to market its once-daily, extended-release fluoroquinolone, ciprofloxacin (Cipro XR), for two new indications: complicated urinary tract infections and acute uncomplicated pyelonephritis.

Among urologic tumor markers, the discovery and application of prostate-specific antigen has established PSA as a vital tool for the early diagnosis, staging, and monitoring of men with prostate cancer.

Edinburgh, Scotland-When used by the same operators in a single center, shockwave lithotriptors of different power generators provide comparable results and have similar complication rates in the treatment of renal stones, urologists at a Scottish stone center reported at the AUA annual meeting.

Older men's sperm is more likely to contain disease-causing genetic mutations, suggests an analysis of sperm from men of various ages by scientists from the McKusick-Nathans Institute for Genetic Medicine at Johns Hopkins University, Baltimore.

Texas patients and physicians scored a major victory when voters approved Proposition 12, a constitutional amendment that authorizes the legislature to determine limitations on non-economic damages in medical liability cases. The vote ratifies the state's recently enacted medical liability reforms.

Patients undergoing surgery in ambulatory surgery centers are safer than those who undergo procedures in doctors' offices, although the relative risk of death or injury is low in both types of facilities, a new Florida study indicates.