Studies of bipolar plasma vaporization of the prostate and thulium vapoenucleation were among the other noteworthy research in BPH/LUTS presented at the AUA annual meeting in Boston.
Doreen E. Chung, MDStudies of bipolar plasma vaporization of the prostate and thulium vapoenucleation were among the other noteworthy research in BPH/LUTS presented at the AUA annual meeting in Boston. The take-home messages were presented by Doreen E. Chung, MD, of New York-Presbyterian, New York.
It seems feasible to use tamsulosin (Flomax) as an over-the-counter medication in men with LUTS. Among men shown a mock-up of drug packaging and asked if the medication would be appropriate for their use, 93% and 98% met appropriate self-selection criteria on unmitigated and mitigated analyses, respectively, and the decision to use tamsulosin appeared appropriate for most men, even among those with low health literacy.
At 5-year follow-up, bipolar plasma vaporization of the prostate (button TURP) appears to be safe and effective, but is associated with a 12% urethral stricture rate and 8% bladder neck contracture rate.
Thulium vapoenucleation appears to be a very durable procedure. At 5 years, medium PSA reduction was 77%, stricture and bladder neck contractor rate was 3%, and 2% of patients required retreatment for recurrent tissue.
A comparison of tadalafil (Cialis), 5 mg daily, with a complementary medicine regimen consisting of three ingredients found no differences in change in International Prostate Symptom Score (IPSS), maximum flow rate (Qmax), and postvoid residual urine volume (PVR), but fewer adverse events were seen with the complementary therapy.
In men with lower urinary tract symptoms (LUTS), transdermal testosterone replacement plus tadalafil, 5 mg daily, versus tadalafil alone showed similar overall improvements in IPSS, Qmax, and PVR, but greater improvements were seen with the combination therapy in quality of life and the IPSS storage subscore.
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