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Dr. Morris on end points beyond survival achieved with 177Lu-PSMA-617 in VISION trial


The phase 3 VISION trial explored the PSMA-targeted therapy 177Lu-PSMA-617 (LuPSMA) in patients with progressive PSMA-positive metastatic castration-resistant prostate cancer. Data presented at the 2021 ASCO Annual Meeting by lead study author Michael J. Morris, MD, showed that adding LuPSMA to standard of care (SOC) led to a nearly 40% reduction in the risk of death versus SOC alone. Adding LuPSMA to SOC also led to a 60% reduction in the risk of disease progression or death.

In this video, Morris, a medical oncologist and section head, Prostate Cancer, GU Oncology, Memorial Sloan Kettering Cancer Center, discusses other key end points reach with LuPSMA in the study, including time to symptomatic skeletal events, rate of PSA decline, and objective response rate (RECIST).

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