Patient Conversations When Initiating ADT for Prostate Cancer

In ‘Patient Conversations When Initiating ADT for Prostate Cance,’ our panel delve into the following question:

1. When initiating ADT, how do you frame discussions around qurality of life, lifestyle modification, and long-term monitoring to help patients commit to and remain on therapy?

The expert urologists and medical oncologistsdiscuss how clinicians counsel patients when initiating ADT, emphasizing the balance between life-prolonging benefit and preservation of quality of life. Faculty highlight common early concerns such as hot flashes, fatigue, muscle loss, bone health, and cardiometabolic risk, with a strong focus on lifestyle interventions—particularly exercise and resistance training—as foundational supportive strategies. The panel also discusses real-world experience with oral ADT, noting that side effects are generally consistent with expectations and manageable through routine monitoring. Finally, the conversation underscores the importance of longitudinal follow-up, as patients are living longer on therapy, often revealing additional health issues that require ongoing vigilance beyond prostate cancer alone.

Our next episode,‘Reducing Cardiovascular Risk Associated with ADT in mCSPC,’ panelists highlight strategies to prevent and manage cardiometabolic risk during ADT, including weight gain, hypertension, dyslipidemia, and diabetes, through lifestyle intervention and proactive monitoring. They also emphasize coordinated care with primary care and cardio-oncology, using risk tools and targeted testing to guide referral and risk reduction.