Scott Sellinger, MD, FACS

In this video, Scott Sellinger, MD, FACS, discusses factors beyond the presence of PTEN deficiency that may influence how clinicians approach capivasertib (Truqap) treatment in metastatic hormone-sensitive prostate cancer.

In this video, Scott Sellinger, MD, FACS, discusses important considerations for urologists who may be prescribing capivasertib (Truqap) for the first time following its approval in PTEN-deficient metastatic hormone-sensitive prostate cancer.

The phase 3 CAPItello-281 trial (NCT04493853) met its primary end point by showing that the addition of capivasertib (Truqap) to abiraterone (Zytiga) and prednisone significantly improved radiographic progression-free survival (rPFS) vs abiraterone and prednisone alone in patients with PTEN-deficient metastatic hormone-sensitive prostate cancer (mHSPC).

In this video, Scott Sellinger, MD, FACS, discusses how PTEN testing may become increasingly integrated into the routine evaluation of patients with newly diagnosed metastatic prostate cancer following the FDA approval of capivasertib (Truqap) for patients with PTEN-deficient disease identified by an FDA-authorized test.

Scott Sellinger, MD, FACS, explains the biologic significance of PTEN loss in metastatic prostate cancer, why it is associated with aggressive disease and poor outcomes, and how the approval of capivasertib has transformed PTEN from a prognostic biomarker into a predictive biomarker with a targeted treatment option.

"The main issue in DC now is the Medicare Physician Fee Schedule," says Scott Sellinger, MD, FACS.

LUGPA president Scott B. Sellinger, MD, FACS, highlights the key priorities and sessions at this year's LUGPA Annual Meeting.

Scott B. Sellinger, MD, FACS, discusses the challenges facing urologists, the loss of telehealth flexibility, and why bipartisan action remains urgent.

Experts summarize how the use of PSMA-PET imaging has impacted the field to date and share their hopes for the future.

The panel discusses the possibility of PSMA-PET becoming the standard-of-care imaging modality for prostate cancer, which may obviate the need for conventional imaging and bone scans, and then touches on the increasing availability of PSMA-targeted radiotherapies.

Drs Cookson and Sellinger discuss the remaining unmet needs in imaging for patients with prostate cancer.

The panel shares their perspectives on the transition to virtual multidisciplinary tumor boards for patients with prostate cancer after the COVID-19 pandemic.

Delving deeper into PSMA-PET results interpretation and information sharing, panelists outline the most critical information needed from radiologists and urologists on a patient’s multidisciplinary care team.

Experts share potential solutions to overcome the clinical challenges of using PSMA-PET in practice, including use of reader training programs.

Dr Cookson discusses the challenges of using PSMA-PET imaging in prostate cancer, including reimbursement and patient access.

Dr Sellinger details the range of clinical guidelines on the use of PSMA-PET imaging in prostate cancer and which he is most likely to follow.

The panel reviews clinical data and provides real-world insight on how use of PSMA-PET imaging has impacted the management of patients with prostate cancer.

Experts discuss practical considerations on selection among available PSMA-PET tracer options for prostate cancer imaging, including regional availability, scheduling, and preparation requirements.

The panel reviews the similarities and differences between the FDA-approved PSMA-PET tracer options for prostate cancer imaging.

Phillip Koo, MD, defines prostate-specific membrane antigen (PSMA) and explains the rationale for use as a target in PET-based prostate cancer imaging.

Scott Sellinger, MD, FACS, shares a historical perspective on use of conventional imaging modalities in prostate cancer.

Michael Cookson, MD, MMHC, explains the NCCN criteria used to stratify patients with clinically localized prostate cancer into risk groups.