Prostate Cancer

Drugs and devices in the pipeline from VIVUS, Auxilium Pharmaceuticals, OncoGenex Pharmaceuticals, Veloxis Pharmaceuticals, OPKO Health, and Oxthera AB.

The makers of the Decipher and ConfirmMDx prostate cancer tests have announced separate agreements that will expand insurance coverage for the two tests.

High-dose supplementation with both selenium and vitamin E increases the risk of high-grade prostate cancer, according to a recent multicenter study. This risk depends upon a man’s selenium status before taking the supplements.

The type of primary treatment received for prostate cancer-surgery or radiation therapy-is the strongest predictor of lesser-known complications such as the need for additional surgical procedures and development of secondary cancers, according to the authors of a recently published study from the University of Toronto.

The second-generation androgen receptor antagonist enzalutamide (XTANDI) significantly improved survival and delayed the time to chemotherapy in men with previously untreated metastatic castrate-resistant prostate cancer, according to a recent study.

Promotion of strategies for the repeal of the sustainable growth rate formula and preservation of access to appropriate PSA screening are among the AUA’s top legislative priorities for 2014, the association announced.

A 46-gene diagnostic test accurately predicted, based on biopsy specimens, which men would develop biochemical recurrence (BCR) or metastatic disease following radical prostatectomy, a recently published study found.

In this article, I outline my patient discussion concerning prostate cancer screening, which includes defining what the PSA test is, why to screen or not to screen, the screening controversy, current guidelines, and decision aids.

Prostate cancer patients treated with androgen deprivation therapy experienced changes in mental and emotional well-being during treatment, although there was no meaningful decline in emotional quality of life 2 years after treatment, a recent study found.

A genomic test capable of predicting the probability of developing metastatic prostate cancer outperformed existing clinical risk factors for predicting biochemical failure and distant metastasis following radiation therapy, researchers reported at the Genitourinary Cancers Symposium in San Francisco.

Separate studies at the Genitourinary Cancers Symposium highlighted the utility of prostate cancer tests Prolaris and ConfirmMDx for Prostate Cancer for treatment planning and identifying aggressive disease, respectively.

The androgen-receptor blocker enzalutamide (XTANDI) increases survival by 29% in men with metastatic castration-resistant prostate cancer (mCRPC) and delays progression of the disease by 81%, according to new phase III study results in men who had not previously received chemotherapy.

Drugs and devices in the pipeline from Medivation, Astellas Pharma, Teva Pharmaceuticals, Boston Scientific, Northwest Biotherapeutics, and Generex Biotechnology.

New products and services from UroGPO, Caldera Medical, Auxilium Pharmaceuticals, VIVUS, and Jeffrey Albaugh, PhD, APRN.

Higher levels of melatonin, a hormone involved in the sleep-wake cycle, may suggest decreased risk for developing advanced prostate cancer, according to a recent study.

Urologists across the country offer their opinions on high-intensity focused ultrasound.

Men who walked at a fast pace prior to prostate cancer diagnosis had more regularly shaped blood vessels in their prostate tumors compared with men who walked slowly, providing a potential explanation for why exercise is linked to improved outcomes for men with prostate cancer.

Type of surgical approach-open or robot assisted-appears to have no effect on specific clinical outcomes in patients undergoing radical prostatectomy for high-risk prostate cancer, nor does the procedure influence the pathway subsequent therapy might follow, according to a recent study.

More than 85% of patients undergoing robot-assisted laparoscopic prostatectomy may not require opioid analgesia either immediately post-op, in hospital, or upon release, according to a recent study.

A lawsuit was filed against both the urologist and the radiologist involved in the treatment of the kidney stone, claiming that he was not informed of the abnormality on the left kidney noted on the CT scan and the recommendation for follow-up.

Both the death rate and incidence rate for prostate cancer continues to decline, according to the latest round of statistics from leading U.S. cancer groups.

Researchers at Fred Hutchinson Cancer Research Center and the University of Washington in Seattle have developed a personalized tool that they say can predict the likelihood of prostate cancer overdiagnosis.

PSA screening has likely played an important role in the 40%-plus drop in prostate cancer mortality since the late 1980s, although the mortality rate for metastatic disease has remained the same, say study authors from the University of California, Davis.

The controversial oil and natural gas drilling technique called hydraulic fracturing, or fracking, uses many chemicals that can disrupt the body’s hormones, according to new research.

Signs of inflammation in a man’s prostate biopsy may indicate that he has a reduced risk of subsequently being diagnosed with prostate cancer in a future biopsy, according to the authors of a recently published study.

Insurance coverage has expanded for an epigenetic test for prostate cancer and percutaneous tibial nerve stimulation (PTNS) for the treatment of overactive bladder (OAB).

The top 10 Urology Times articles of 2013 encompass topics including prostate biopsy, the urology work force, and PSA screening.

The latest products and services from Lambert Academic Publishing, the AUA, United Guardian, and SpryPublishing.

With a deluge of new drug treatments for advanced prostate cancer on the market, a care model emphasizing urologist and medical oncologist collaboration is needed, according to an article whose authors represent each specialty.

Risk classification changed in more than half of prostate cancers following assessment of cell cycle progression in tumors, according to a study reported at the Society of Urologic Oncology meeting in Bethesda, MD.