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A particular signature set of inherited characteristics and mutations in mitochondrial DNA (mtDNA) significantly increases the risk of kidney and prostate cancers in men, according to a presentation at the American Association of Cancer Research annual meeting in Anaheim, CA.

Tamoxifen (Nolvadex) reduces the frequency of gynecomastia and breast pain in prostate cancer patients taking bicalutamide (Casodex), according to a study in Lancet Oncology (2005; 6:295-300).

For the third straight year, Urology Times will bring readers E-news Daily Meeting Report--free daily news updates from the upcoming AUA annual meeting in San Antonio, delivered directly to your e-mail box.

No patient has developed urinary retention or elevated post-void residuals following our modified injection technique.

Links to many manufacturers exhibiting at the 2005 American Urological Association meeting in San Antonio. Exhibit Hall booth numbers have been included so that you can find items and exhibits of particular interest to you.

Istanbul, Turkey--Nearly half of men with self-described erectile dysfunction report the occurrence of premature ejaculation either "always" or "frequently," according to data from the Men's Attitudes to Life Events and Sexuality (MALES) study.

Istanbul, Turkey--Chronic prostatitis appears to be significantly associated with psychological disorders, such as depression, anxiety, and panic, according to the results of a German study. The study also found that pelvic pain symptoms are far less prevalent than expected (3.2%), while the mean age of afflicted men was significantly higher than noted in previous trials (60.6 years).

Istanbul, Turkey--Prostate inflammation significantly raises the risk of clinical progression in men with lower urinary tract symptoms and BPH, according to a first-time investigation into the impact of acute and/or chronic inflammation on men with BPH. The most significant impact of acute or chronic inflammation was an increased risk of acute urinary retention, particularly in patients receiving placebo, according to the analysis, based on a subset of patients from the Medical Therapy of Prostatic Symptoms (MTOPS) patient cohort.

Istanbul, Turkey--Transurethral microwave thermotherapy of the prostate offers a 50% improvement in pain in up to two-thirds of patients with chronic prostatitis/chronic pelvic pain syndrome, which is comparable to other treatment modalities, according to researcher Christof Kastner, MD, PhD. The therapy also appears to promise good durability 2 years post-procedure.

No patient has developed urinary retention or elevated post-void residuals following our modified injection technique.

Orlando, FL--How likely are patients who have undergone radical prostatectomy to present with rising PSA levels and subsequent metastatic progression? Researchers at Memorial Sloan-Kettering Cancer Center employ a computerized tool called a nomogram to find the answer.

Orlando, FL--The management of localized prostate cancer has undergone a significant, dramatic shift in recent years. Both pure and robot-assisted laparoscopic prostatectomy appears to be a viable treatment option that is popular with patients; watchful waiting has declined, despite the stage migration seen in the PSA era; and hormonal therapy has become more widely used in low-risk patients, a source of controversy.

Washington--Both physicians and Medicare beneficiaries are in for a jolt next year, according to government officials who indicated in late March that Medicare will slash physician payments by 4.3% in 2006 and slap beneficiaries with an $11 per month premium increase.

Abundant choices for any budgetFrom Caribbean and Continental to Southwest fare and seafood, restaurants in San Antonio offer an abundance of choices to suit your taste and budget.Below is a list you can refer to during the AUA annual meeting. Urology Times thanks San Antonio urologists Allen Morey, MD, Juan Reyna, MD, Michael Sarosdy, MD, and Ritchie Spence, MD, for commenting on some of their favorite area restaurants.Note that the area code for all restaurants in 210.

Montreal--Phosphodiesterase type-5 inhibitors appear to be effective in treating erectile dysfunction in men who are also receiving pharmacologic treatment for depression. A retrospective study presented here at the Canadian Psychiatric Association annual meeting that looked specifically at tadalafil (Cialis) demonstrated that the drug was effective in improving erections and achieving intercourse in this population.

Anti-inflammatory drugs, either alone or in combination with an alpha-blocker or 5-alpha-reductase inhibitor, may have an important role in treating or possibly even preventing the progression of BPH.

Orlando, FL--What are the benefits of combining castration with a nonsteroidal antiandrogen in the treatment of advanced prostate cancer? Laurence Klotz, MD, of the University of Toronto, has found a high probability that bicalutamide (Casodex), 50 mg/day, plus castration provides a survival advantage over castration alone.

Orlando, FL--Testosterone's effect on the development and progression of BPH and prostate cancer is well known, but a group of University of Tennessee researchers has been focusing on testosterone's less frequently studied "partner in crime"—estrogen.

Hormone therapy increased the incidence of all types of incontinence at 1 year among women who were continent at baseline.

Orlando, FL--A genetically modified vaccine has demonstrated immunogenicity and clinical activity in hormone-refractory prostate cancer patients with metastatic disease, researchers reported in a poster presentation at the 2005 Multidisciplinary Prostate Cancer Symposium.

There's no better way, after physician referrals, to generate new patients than public speaking.

The average intravaginal ejaculatory latency time of premature ejaculation sufferers is 1.8 minutes, versus 7.3 minutes in men without PE, according to a large epidemiologic study published in The Journal of Sexual Medicine (2005; 2:358).

AUA has appointed Kathryn Bell as the scientific education program manager in its Office of Education.

The average intravaginal ejaculatory latency time of premature ejaculation sufferers is 1.8 minutes, versus 7.3 minutes in men without PE, according to a large epidemiologic study published in The Journal of Sexual Medicine (2005; 2:358).

The American College of Surgeons has published a new 200-page manual designed to guide surgeons in evolving areas of patient safety.

An agent under investigation for treatment of overactive bladder demonstrated statistically significant improvements over placebo in phase III trials, according to Schwarz Pharma, which is developing the drug, fesoterodine.

The American Foundation of Urologic Disease will be under the ageis of the American Urological Association following an agreement between leaders of the two groups.

Steep Medicare payment cuts to physicians and other health professionals will hurt access to care for America's seniors and disabled, according to a survey of physicians by the American Medical Association.