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Opinion|Videos|February 24, 2025

Current and Emerging Treatment Landscape of mHSPC

Jack Andrews MD; Eugene Cone, MD; and Arash Rezazadeh, MD, discuss how metastatic hormone-sensitive prostate cancer presents clinically, explore current treatment standards including combination therapies, evaluate emerging data from the ARANOTE trial on darolutamide efficacy, consider quality of life factors in treatment selection, and examine how novel therapeutic approaches may reshape future care pathways.

Timecodes

1:54 mHSPC and Imaging

4:57 Current SOC in mHSPC

10:15 Choosing Therapy in mHSPC

18:51 ARANOTE Trial in mHSPC

21:15 Experience With ARI

27:08 Emerging mHSPC Treatments

32:51 ARANOTE Subgroup Analysis

35:31 Future Outlook for mHSPC

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