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Dr. Sadeghi on research into neurogenic bladder

"My goal as a 'plumber'/urologist is to see if we can find better options and also understand the mechanism behind the disease," says Zhina Sadeghi, MD.

In this video, Zhina Sadeghi, MD, discusses her work on researching neurogenic bladder. Sadeghi is a UCI Health urologist and assistant professor of urology at UCI School of Medicine.

Transcription:

What do you feel is underreported or underappreciated in your field of expertise?

As I mentioned, I'm also a part of a national neurogenic bladder research group. We are a group of neurourologists across the United States. We have come together to be able to facilitate big multicenter clinical trials on patients with neurogenic bladder. That means bladders with spinal cord injury issues, multiple sclerosis, Parkinson's, any neurological issue that impacts the bladder, and we do have that in the society; a big proportion of our neurogenic patients have neurogenic bladder issues like retention; they leak urine, they have urgency, they may not be able to have a safe bladder for the kidneys to stay safe. So there are few trials right now we are running on patients with multiple sclerosis, both on neuromodulation of their bladder and also understanding the relationship between the level of their lesion in the central nervous system compared with bladder symptoms, and we are running those in collaboration with the University of Michigan. We also do have another interesting study we are running with Houston Methodist Hospital and we are working on finding a biomarker in the urine of patients with spinal cord injury that can help us predict if this patient would deteriorate fast with their bladder or are they going to be responsive to neuromodulation treatment? We are basically having a multi arm study going on with this. These are all very exciting for me. My goal as a "plumber" urologist is to see if we can find better options and also understand the mechanism behind the disease that are going around the urinary tract system; either it's a bladder or urethra.

This transcription was edited for clarity.

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