
Opinion|Videos|May 12, 2025
Factors Contributing to Higher Incidence and Worse Outcomes of mHSPC in Black Men
Author(s)Quoc-Dien Trinh, MD, MPH
A panelist discusses how the differences in prostate cancer among Black men are multifactorial, including biological differences in risk alleles, social determinants of health, and limited access to care and clinical trials.
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Episodes in this series

Multifactorial Causes of Racial Disparities
Key Themes:
- Disparities have complex, multifactorial origins.
- Biological differences include potentially different risk alleles in African American men.
- Social determinants of health significantly impact outcomes.
- Access to care, including clinical trials, remains problematic for Black men.
Key Points for Physicians:
- Consider biological and social factors when managing Black patients.
- Address potential socioeconomic barriers to treatment adherence.
- Facilitate clinical trial access when appropriate treatment options exist.
Notable Insights: The combination of biological differences and socioeconomic factors creates a complex landscape requiring multifaceted interventions at individual and systemic levels.
Clinical Significance: Understanding the interplay between biological and social factors is essential for developing effective strategies to reduce prostate cancer disparities in Black men.
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