Translating the Trial: How Findings from ARANOTE May Inform Treatment Decisions

Clinical Implications for Patient Care

Key Themes:

• Study findings directly inform the treatment of Black men with prostate cancer.
• Results confirm drug efficacy in this specific population.
• Data support equal eligibility of Black men for darolutamide treatment.
• Findings provide reassurance regarding a comparable benefit-risk profile.

Key Points for Physicians:

• Confidently recommend darolutamide to eligible Black patients.
• Use these data to address potential concerns about efficacy in diverse populations.
• Reassure patients regarding a comparable benefit-risk profile across racial groups.

Notable Insights: These findings provide clinicians with specific, evidence-based information to address potential concerns from clinicians and patients about treatment efficacy in Black men.

Clinical Significance: The confirmed efficacy and safety in Black men support equitable treatment recommendation practices and may help reduce disparities in advanced therapeutic approaches.