Integrating PSMA PET into Advanced Prostate Cancer Care

In the final episode, ‘Advice for Integrating PSMA PET Imaging in Advanced Prostate Cancer,’ the panelists share practical advice for incorporating PSMA PET into prostate cancer clinics and workflows. Clinicians emphasize that PSMA PET offers superior sensitivity and specificity compared with conventional imaging, particularly for high-risk disease, biochemical recurrence, and determining eligibility for radioligand therapy. The discussion highlights how PSMA PET can meaningfully influence management decisions, including adaptive approaches to radioligand therapy based on interim imaging and PSA response. Faculty also address the importance of multidisciplinary collaboration, particularly with radiation oncology, when evaluating limited metastatic disease and considering radiation strategies. Finally, the group underscores the need for careful interpretation and clear reporting language, recognizing common pitfalls and the importance of reducing unnecessary patient anxiety in advanced prostate cancer.