Opinion|Videos|April 24, 2026

Multidisciplinary Interpretation of PSMA PET in Advanced Prostate Cancer

PSMA PET scans reshape prostate cancer care—learn who should interpret results, how reports vary, and why a team approach guides treatment.

Multidisciplinary Interpretation of PSMA PET in Advanced Prostate Cancer’, Dr. Neal Shore focuses on the collaborative nature of interpreting PSMA PET imaging and integrating findings in advanced prostate cancer care. While PSMA PET scans are typically interpreted by nuclear medicine physicians or radiologists, the responsibility for applying these results to clinical decision-making extends across multiple specialties, including urology, medical oncology, and radiation oncology. As PSMA PET technology continues to evolve with increasing accuracy and a growing number of tracer options, ensuring high-quality interpretation and standardized reporting has become a critical priority.

The discussion emphasizes that interpretation is not a single-step process but involves multiple layers, including image acquisition, formal reporting, and subsequent clinical interpretation by the treating team. Variability currently exists in how PSMA PET findings are reported and communicated, which may depend on institutional practices, geographic location, and the clinician’s level of familiarity with the technology. As a result, there is an ongoing learning curve across specialties as clinicians work to better understand how to interpret imaging findings and incorporate them into patient care.

The next episode in this series, ‘Impact of PSMA PET on Treatment Selection in Advanced Prostate Cancer,’ features Dr. Neal Shore examines the evolving and variable standards for interpreting PSMA PET imaging in advanced prostate cancer. Improved consistency in reporting and multidisciplinary collaboration are critical to optimizing treatment decisions and disease management.