Opinion|Videos|June 13, 2024

Intravesical Novel Therapy for HR BCG-Unresponsive NMIBC

Gary D. Steinberg, MD, analyzes data from the BOND-003 study presented at AUA 2024, which investigated the use of intravesical cretostimogene grenadenorepvec for treating high-risk, BCG-unresponsive non-muscle invasive bladder cancer with carcinoma in situ, and discusses the mechanism of action of this novel oncolytic viral therapy.

Episodes in this series

Video content above is prompted by the following question(s):

  • Interim data from BOND-003 were just recently presented during the AUA 2024: (A Phase 3, Single-arm Study of Intravesical Cretostimogene Grenadenorepvec for the Treatment of High Risk, BCG-Unresponsive Non-Muscle Invasive Bladder Cancer with Carcinoma in Situ).
    • What is the mechanism of action of cretostimogene?

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