The Logistical Challenges in ccRCC Treatment

Practical Considerations for Implementation

Main Discussion Topics:

• Logistical challenges requiring separate appointments for tracer administration and imaging
• Imaging window is 5 days (± 2 days) after tracer injection.
• Long half-life (78 hours) provides flexibility in scheduling
• Comparison with prostate-specific membrane antigen tracers, which require same-day imaging.

Key Points for Physicians:

• Requires 2 separate patient visits: one for tracer injection, another for imaging.
• A 5-day interval between injection and imaging (with 2-day flexibility)
• A 96-hour shelf life provides scheduling flexibility.
• Noninvasive approach compared with biopsy with comparable diagnostic performance

Notable Insights:

Despite logistical considerations requiring 2 visits, the experts view this as a “virtual biopsy,” with performance characteristics similar to actual tissue sampling but without invasiveness.

Clinical Significance:

The logistical requirements are outweighed by the potential clinical value and noninvasive nature of the test compared with biopsy alternatives.