Opinion

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The Logistical Challenges in ccRCC Treatment

Panelists discuss how the logistical challenge of the new test requiring separate appointments (tracer injection followed by imaging 5 days later) is offset by scheduling flexibility because of the tracer’s 78-hour half-life and the technology essentially providing a “virtual biopsy” without invasive procedures.

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      Practical Considerations for Implementation

      Main Discussion Topics:

      • Logistical challenges requiring separate appointments for tracer administration and imaging
      • Imaging window is 5 days (± 2 days) after tracer injection.
      • Long half-life (78 hours) provides flexibility in scheduling
      • Comparison with prostate-specific membrane antigen tracers, which require same-day imaging.

      Key Points for Physicians:

      • Requires 2 separate patient visits: one for tracer injection, another for imaging.
      • A 5-day interval between injection and imaging (with 2-day flexibility)
      • A 96-hour shelf life provides scheduling flexibility.
      • Noninvasive approach compared with biopsy with comparable diagnostic performance

      Notable Insights:

      Despite logistical considerations requiring 2 visits, the experts view this as a “virtual biopsy,” with performance characteristics similar to actual tissue sampling but without invasiveness.

      Clinical Significance:

      The logistical requirements are outweighed by the potential clinical value and noninvasive nature of the test compared with biopsy alternatives.

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