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Current Unmet Needs in ccRCC Diagnosis

Imaging advancements in ccRCC are crucial for predicting tumor biology and enhancing treatment strategies through molecular imaging techniques.

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      Current Gaps in Renal Mass Imaging

      Main Discussion Topics:

      • Current imaging cannot reliably predict tumor biology or aggressiveness.
      • Need for imaging techniques that can identify aggressive lesions requiring immediate intervention
      • Comparison to advances in prostate cancer with molecular imaging (prostate-specific membrane antigen [PSMA] PET)
      • Desire for similar molecular imaging paradigms in kidney cancer

      Key Points for Physicians:

      • Contemporary imaging provides anatomic and enhancement information but limited biological insights.
      • The ability to predict which tumors will become aggressive remains a significant gap.
      • Prostate cancer imaging has evolved to routinely include molecular imaging (PSMA PET).
      • Similar developments are needed in kidney cancer imaging.

      Notable Insights:

      There is a significant need for imaging that predicts biological behavior rather than just providing anatomic information.

      Clinical Significance:

      Developing imaging that predicts tumor biology could prevent overtreatment of indolent tumors and ensure appropriate intervention for aggressive ones.

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