Treatment advances for overactive bladder 'pushing the therapeutic index'

Chicago-Some researchers investigating the physiology and treatment ofoveractive bladder have questioned whether a "therapeutic ceiling"has been reached with anticholinergic medications, the current mainstayof treatment. Although the balance between efficacy and tolerability ofanticholinergics falls short of ideal, a number of products under developmenthold promise, said Roger Dmochowski, MD, professor of urology at VanderbiltUniversity School of Medicine in Nashville, TN.