Orlando, FL--A genetically modified vaccine has demonstrated immunogenicity and clinical activity in hormone-refractory prostate cancer patients with metastatic disease, researchers reported in a poster presentation at the 2005 Multidisciplinary Prostate Cancer Symposium.
There's no better way, after physician referrals, to generate new patients than public speaking.
An agent under investigation for treatment of overactive bladder demonstrated statistically significant improvements over placebo in phase III trials, according to Schwarz Pharma, which is developing the drug, fesoterodine.
Yamanouchi Pharmaceutical Co., Ltd., and Fujisawa Pharmaceutical Co., Ltd., merged to form a new corporation named Astellas Pharma, Inc.
Within 36 hours after ingesting sildenafil citrate (Viagra) for erectile dysfunction, some men have nonarteritic anterior ischemic optic neuropathy (NAION), described as "stroke of the eye," according to a report of seven cases published in the Journal of Neuro-ophthalmology (2005; 25:9-13).
A clinical study evaluating the effect of co-administration of an investigational intranasal agent PT-141 and sildenafil citrate (Viagra) shows positive results in patients with erectile dysfunction, according to researchers from Palatin Technologies Inc. and King Pharmaceuticals Inc.
The FDA has approved triptorelin pamoate for injectable suspension (Trelstar Depot, 3.75 mg, and Trelstar LA 11.25 mg). The sustained-release, 1- and 3-month intramuscular injectable formulations are now available nationwide for the palliative treatment of advanced prostate cancer when orchiectomy or estrogen administration are either not indicated or are unacceptable to the patient.
Antimuscarinics are recommended as first-line pharmacotherapy for OAB. They act to reduce urgency, stabilize detrusor overactivity, and increase bladder capacity.
Philadelphia--Urologists who manage patients with overactive bladder are challenged not only with choosing from a growing list of pharmacologic treatment options, but also with the prospect that some patients may not respond to oral anticholinergic treatment at all. In these patients with "refractory detrusor overactivity," it is important to realize that a number of factors mitigate against successful therapy, said Roger R. Dmochowski, MD, professor of urology at Vanderbilt University Medical Center, Nashville, TN.
Washington--A controversy is brewing over whether Medicare should pay for erectile dysfunction drugs, which boiled over in the midst of heated discussions over the cost of the new Medicare drug benefit. Now estimated at $720 billion, the expected cost of the program is nearly double the government's original 2003 projections.
Irvine, CA-- The Pathway Ureteral Access Device from Onset Medical allows minimally invasive ureteral access in a manner that is less traumatic to both the kidney and ureteral tract. The device, which recently received FDA approval, is designed to eliminate a number of surgical maneuvers.
[Unit investment trusts] differ from mutual funds in that they are a collection of specific stocks or bonds not actively managed once they are purchased as an investment.
Honolulu--Photoselective vaporization of the prostate (PVP) is a safe, efficacious approach to relieve lower urinary tract symptoms, according to a study presented at the annual Kimbrough Urological Seminar here. PVP engenders minimal morbidity while achieving significant cost savings, said study author Robert E. Reiter, MD.
Orlando, FL--A novel immunotherapy drug may increase the survival of hormonally refractive patients with asymptomatic, metastatic prostate cancer, according to the results of a small study with great promise.
Trospium chloride (Sanctura) does not affect sleep patterns in patients aged 51 to 65 years, according to a study published in the British Journal of Urology (2005; 95:346-9).
Men receiving androgen deprivation therapy for prostate cancer might notice a reduction in verbal fluency, visual recognition, and visual memory, according to a small trial published in the Feb. 28 online edition of Cancer.
If finasteride (Proscar) were prescribed prophylactically in older men, an estimated 316,760 years of life over 10 years would be saved through the prevention of prostate cancer, according to a new analysis of data from the Prostate Cancer Prevention Trial (PCPT).
A new National Institutes of Health-funded study is recruiting adults newly diagnosed with either painful bladder syndrome or interstitial cystitis to determine if the antidepressant amitriptyline (Elavil) will reduce the pain and frequent urination associated with the conditions.
A new National Institutes of Health-funded study is recruiting adults newly diagnosed with either painful bladder syndrome or interstitial cystitis to determine if the antidepressant amitriptyline (Elavil) will reduce the pain and frequent urination associated with the conditions.
Leuprolide acetate (Eligard), 45 mg, is now commercially available in the United States for the palliative treatment of advanced prostate cancer patients, according to its marketer, Sanofi-Aventis, Bridgewater, NJ.
The fluoroquinolone ciprofloxacin (Cipro) appears to be more effective than amoxicillin-clavulanate (Augmentin) as a treatment for acute uncomplicated urinary tract infections in women, even in those infected with susceptible strains, according to a study published in last week's JAMA (2005; 293:949-55).
APC8015 (Provenge), an investigational form of immunotherapy, significantly improves survival in men with asymptomatic, metastatic androgen-independent prostate cancer compared with patients receiving placebo, according to a study being hailed as the first to show a survival benefit with a vaccine in patients with advanced prostate cancer.
A number of questions still surround coding and reimbursement for in-office drug injections. As a result, this article will take a slightly different approach, using a "frequently asked questions" format. I?ll repeat the questions I?ve been asked about the new drug payments at seminars and via phone and e-mail, and attempt to give you straight answers to the best of my understanding.
The ideal management strategy for correction of ureteropelvic junction (UPJ) obstruction remains undefined. Open pyeloplasty for correction of UPJ obstruction was first described by Anderson and Hynes over a century ago and remains the gold standard against which we must compare all alternative therapies.
Washington—A majority of recurrent urinary tract infections in women are caused by Escherichia coli bacterial persistence or reinfection with the originally infecting E coli strain, according to findings from a Danish study presented at the Interscience Conference on Antimicrobial Agents and Chemotherapy.
