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The AUA take-home messages on management of advanced prostate cancer underscore research interest in better defining the risks and benefits of androgen deprivation therapy (ADT) and provide some encouragement that new methods for treatment and evaluation will be available in the future to fill important gaps.

While it does not affect the vast majority of male infertility patients, a subgroup of men with disrupted hormonal axes and/or hypogonadism should be worked up for the presence of osteopenia.

Prostate cancer patients treated by highly experienced surgeons are much more likely to be cancer-free 5 years after surgery than patients treated by surgeons with less experience, according to a study to be published in the Journal of the National Cancer Institute.

Based on the relative risk to siblings, 80% of kidney cancer cases are likely to occur in 20% of the population with the highest genetic risk, indicating the importance of further investigation of genetic factors in cancer prevention, according to a European multicenter, case-control study.

High intake of cruciferous vegetables, including broccoli and cauliflower, may be associated with reduced risk of aggressive prostate cancer, particularly extraprostatic disease, suggests a study to be published in the Journal of the National Cancer Institute.

Results of a retrospective, inter-institutional study comparing outcomes of patients with urothelial carcinoma of the bladder highly favor the use of an extended template for bilateral pelvic lymph node dissection (PLND) when performing radical cystectomy.

The primary message from a study evaluating long-term urothelial recurrence and disease-specific survival after radical nephroureterectomy for upper tract transitional cell carcinoma is that there remains a critical need for better methods to enable early diagnosis.

A two-step transurethral resection (TURB) procedure in patients with superficial transitional bladder cancer, already part of practice guidelines in Germany, appears to improve patient outcomes by identifying positive tumor beds that may require a second TURB.

Unless Congress steps in again, physicians participating in the Medicare program will see their fees reduced by an average of 9.9% for 2008, a move that already has prompted a call for action from the American Medical Association.

Mountain View, CA-Percutaneous Systems' telescopic PercSys Accordion stone management device is a microcatheter equipped with a multi-fold film occlusion at the distal end. Once deployed, the occlusion conforms to and fills the ureter, preventing retrograde stone fragment migration into the kidney.

Increasing evidence has recently pointed toward a relationship between LUTS secondary to BPH and the presence of metabolic syndrome. This relationship has been supported by recent epidemiologic findings.

Adjuvant bacillus Calmette-Guerin appears to provide no benefit for improving the oncologic outcome of patients with upper tract transitional cell carcinoma undergoing nephroureterectomy.

A multi-institutional retrospective analysis has identified five variables that independently predict cancer-specific survival in patients with nonmetastatic transitional cell carcinoma of the upper urinary tract.

As new AUA president, Paul Schellhammer, MD, has listed three primary priorities for the association in 2007-08: innovation (research), education, and application (health policy).

Recently released FDA regulations requiring current good manufacturing practices for dietary supplements take an important first step in ensuring the quality of supplements, but fall short of making manufacturers accountable for the products' safety and efficacy, according to urologists familiar with the regulations.

Practitioners who specialize in urology, who are male, who seldom order PSA tests, and who are affiliated with specific hospitals are more likely than are other medical practitioners to inappropriately order a PSA test for asymptomatic patients over age 75 years or under age 40, according to a study from the Massachusetts Veterans Epidemiology Research and Information Center.