Interpreting PSA Trends in Patients Receiving Darolutamide Plus ADT With mHSPC

Clinical Implications for PSA Monitoring

Key Themes:

• Real-world implications for urologists monitoring patients on darolutamide plus ADT
• Importance of sensitive PSA assays
• Potential for PSA kinetics to guide treatment decisions

Expert Insights:

• Dr Shore provided guidance on how these findings might influence the way urologists monitor and interpret PSA trends in patients receiving darolutamide plus ADT.

He emphasized the importance of using appropriately sensitive assays and how PSA kinetics could inform treatment intensity or surveillance strategies.