Benjamin P. Saylor, Strategic Content Lead

The investigators reported that ultra-low PSA responses “were associated with prolonged rPFS and delayed progression to mCRPC and PSA progression.”

The study population was able to avoid 952 cystoscopies and 70 CT scans, according to the investigators.

No device- or procedure-related serious AEs were observed through 12 months across the entire study population

The investigators reported that treatment with darolutamide reduced the risk of radiological progression or death by 49% in Black men.

The investigators reported a median stone clearance of 96.44%.

In cohort A, the cystectomy-free rate at 36 months was 84%.

More than 80% of patients in both groups had a full recovery of testosterone.

"I would argue that UGN-102 may very well represent a well-tolerated alternative to TURBT as primary treatment for patients with low-grade disease,” says Sandip M. Prasad, MD, MPhil.

The investigators reported that the median Kaplan-Meier estimate of DOR was 24.2 months.

"97% [of patients] remain progression free, and 84.5% avoided cystectomy, highlighting cretostimogene’s bladder-sparing potential,” said Mark D. Tyson II, MD, MPH.

“In the patients with CIS, the probability of a continued complete response at 36 months was 92% vs 67.7%," said Neal D. Shore, MD, FACS.

Treatment with TARA-002 was associated with a 100% high-grade CR at any time in BCG-unresponsive participants.

Clarius Mobile Health said it will be demonstrating the application at the AUA Annual Meeting in Las Vegas, Nevada.

“Oftentimes, [during] the very first visit, we are talking a lot. I am learning what's going on with them," says Anna Myers, CNP.

Take a look through several of the notable phase 3 trials in progress that will be spotlighted at AUA 2025.

The use of onabotulinumtoxinA (onabotA, Botox) for the treatment of overactive bladder comes with several important considerations.

“Like any disease state, you want to make sure you have the right diagnosis; otherwise, you're not going to have a successful treatment plan," says Karyn S. Eilber, MD.

We preview several noteworthy P2 presentations in the urologic oncology space.

“You absolutely need to have a CT scan prior to the surgery to best identify and really intimately understand the kidney’s anatomy," says Perry Xu, MD.

Merrill discusses the evolving non–muscle invasive bladder cancer treatment space.

"There really wasn't a difference in in surgical outcomes. The patients tolerated it very well,” says Joshua J. Meeks, MD, PhD.

Christian Gratzke, MD, explains why an app shows promise for patients with lower urinary tract symptoms.

“The benefit of being here at the University of Minnesota is that we have a bunch of different types of settings to be able to trial this," says Hailey Frye.

“I feel a lot of providers, with Antiva being available, have unfortunately reserved use of this great FDA-approved agent for BCG-unresponsive patients because of the supply issue with BCG," says Suzanne B. Merrill, MD, FACS.

Betty Wang, MD, provides insight on 3 presentations that she believes “may be game changing” in urology.

"We can improve urinary tract infections considerably with behavioral modification," says Anna Myers, CNP.

“I would say the take-home message for this study is that prescribing tamsulosin for a week prior to an anticipated surgery that involves flexible ureteroscopy is a very simple practice that certainly is within standard of care within pediatric urology," says Kate H. Kraft, MD, MHPE, FACS, FAAP.

“It definitely makes it easier for providers [to counsel patients]," says Landon Trost, MD.

“When I talk to physicians outside of urology, as well as within urology, much of the hesitation with using Cost Plus Drugs is that it seems complicated to use, when in reality, the process is actually very simple," says Raymond Xu, MD.