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The FDA’s approval of enzalutamide (XTANDI) to treat metastatic castration-resistant prostate cancer (CRPC) in the pre-chemotherapy setting is a potential game changer for both patients and treating physicians, especially urologists, according to leaders in the prostate cancer field.

The month of September has seen two notable appointments in academic urology, with David F. Penson, MD, MPH, and James McKiernan, MD, both named to department chair positions.

I was driving home from the office last week and realized that I have now been in the "real world" for over a year. As I looked back on the last year, I thought I would share a few of the lessons I've learned as I am curious if others have had a similar experience during their transition from residency to private practice.

Physical activity lowers men’s risk of developing nocturia and should be recommended to patients with the condition, a leading men’s health expert and Urology Times Editorial Council member says.

Metastatic castration-resistant prostate cancer patients whose tumors contain the androgen receptor (AR)-V7 splice variant are less likely to respond to enzalutamide (XTANDI) and abiraterone acetate (ZYTIGA), recent study results indicate.

Low testosterone is often blamed for a lower sex drive and potentially dangerous fat accumulation in men, however researchers from Massachusetts General Hospital report that a lack of estrogen is also to blame. Video provided by Renal & Urology News.

Physicians, including urologists, now have another headache to deal with-making certain information about them published on the Internet by as part of the National Physician Payment Transparency Program (Open Payments) is accurate and not misleading to patients who want to know about the financial benefits their doctors receive from manufacturers of drugs, devices, and biologic and medical supplies.

This video presents a thorough description of all the treatment options available for erectile dysfunction, including their administration, benefits, and limitations.

In this first installment of UrologyTimes.com's new video section, called ‘Y’tube, we present videos from high-volume prosthetic surgeons performing inflatable penile prosthesis (IPP) placement and discussing diagnosis and management of ED. William O. Brant, MD, offers the following general commentary about these procedures, as well as specific comments in the text accompanying each individual video.

In these videos, H. Ballentine Carter, MD, discusses the evidence supporting active surveillance, and Leonard S. Marks, MD, and colleagues outline which men are good candidates for surveillance.

Results of a study that included approximately 50,000 patients point to an association between kidney stones and incident cardiovascular disease and stroke.

Men who eat over 10 portions a week of tomatoes have an 18% lower risk of developing prostate cancer, according to a newly published study from the United Kingdom.

As it becomes apparent that more prostate cancers are clinically insignificant than previously believed, the role of active surveillance in the management of men with low-risk prostate cancer merits expansion.

This letter to the editor is in response to an editorial by J. Stuart Wolf, Jr., MD (“Robotic radical nephrectomy: Really?,” July 2014, page 6). The editorial concerned the article, “Use of robotic RN rising, despite unclear advantages” (July 2014, page 9).

Steven A. Kaplan, MD, introduces #LetsTalkMensHealth, a novel new section in Urology Times focused on men’s health.

Other products featured include a testosterone gel, exercise program to strengthen male pelvic muscles, and a book about prostate cancer diagnosis and management.

Transrectal ultrasound-guided prostate biopsy is associated with a rising rate of hospitalization for urinary tract infection, new study results indicate.

Patients with interstitial cystitis/bladder pain syndrome who have low bladder capacity have a significantly different gene expression profile than both IC/BPS patients with normal bladder capacity and those without the condition, researchers reported in a recently published pilot study.

Presentations of phase III data at the American Society of Clinical Oncology annual meeting in Chicago further support the conclusion that the oral androgen receptor inhibitor enzalutamide (XTANDI) addresses an unmet therapeutic need for metastatic castration-resistant prostate cancer in the pre-chemotherapy setting.

A recent study confirms that treatment choices for localized prostate cancer are not stagnant but continue to evolve, writes Leonard G. Gomella, MD.

A retrospective evaluation to determine adherence to the AUA clinical practice guideline for the management of lower urinary tract symptoms/BPH among urologists practicing in an academic setting found generally positive results, but with room for improvement, researchers reported at the AUA annual meeting in Orlando, FL.

The question of what role urologists should play in managing hormone-resistant prostate cancer is "controversial," says Kenneth Jacobsohn, MD.

In this interview, Stacy Loeb, MD (@LoebStacy), discusses why urologists should participate in Twitter, how it can benefit your daily practice, and some practical “dos and don’ts.”

Sexual function in men with lower urinary tract symptoms/BPH generally declines over time whether or not they are treated with medication. However, the magnitude of worsening differs depending on the treatment received, according to findings from the Medical Therapy of Prostatic Symptoms study.

Photoselective vaporization of the prostate is non-inferior to transurethral resection of the prostate in men with benign prostatic obstruction, researchers reported at the European Association of Urology annual congress in Stockholm, Sweden.

Use of surgery has increased steadily among all men with clinically localized prostate cancer, and in those with low-risk disease, brachytherapy utilization has declined.

As a number of common urologic surgeries have shifted from the inpatient to outpatient setting, potentially preventable deaths have increased following complications, the authors of a recently published study reported.

A significant number of older men with limited life expectancy continue to undergo routine prostate cancer screening, researchers say.

In this article, Robert A. Dowling, MD, discusses practical aspects of a work flow analysis in your office, including its relationship with health information technology and some helpful resources and tools.

The Centers for Medicare & Medicaid Services proposed changes to Medicare payment cover the Physician Quality Reporting System, value-based payment modification, potential relative value unit changes, targeted codes, and a change in global for future years, among other items.