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In just 18 patients, a multicenter phase Ib trial of an intravesical lidocaine-delivery device, called LiRIS (lidocaine-releasing intravesical system), not only knocked down pain and other symptoms for the 2 weeks the device was in the bladders of severely symptomatic patients, but in addition, the effects lasted 4 weeks and longer for many patients.

Physicians should discuss the benefits and risks of PSA testing with their asymptomatic male patients who have life expectancies of greater than 10 years, but the risks outweigh the benefits of men with shorter life expectancies, according to a new evidence-based provisional clinical opinion on prostate cancer screening issued by the American Society of Clinical Oncology.

Loyola University Health System in Maywood, IL has opened a multidisciplinary center to treat women with pelvic floor disorders.

Use of cranberry-containing products appears to be associated with prevention of urinary tract infections in some individuals, according to a meta-analysis published in the Archives of Internal Medicine (2012; 172:988-96).

The diabetes drug pioglitazone (Actos) was associated with a 22% increased risk of developing bladder cancer in a recent study, supporting earlier research findings of a link between the drug and bladder cancer.

American Medical Systems (Minnetonka, MN) has signed a co-development agreement with Allergan, Inc. to jointly develop and seek regulatory approval for the delivery of onabotulinumtoxinA (Botox) using the AMS JetTouch system for treatment of overactive bladder.

A recent study has pinpointed four genes linked to prostate cancer, a finding that researchers say could significantly improve diagnosis and treatment by identifying slow-growing cancers that do not need to be treated and by developing targeted therapies for aggressive forms of the disease.

The FDA recently granted pre-market approval to Prostate Health Index (phi), a noninvasive blood test that manufacturer Beckman Coulter, Inc. claims is 2.5 times more specific in detecting prostate cancer than PSA in patients with PSA values in the 4.0 to 10.0 ng/mL range.

The American Institute of Ultrasound in Medicine (AIUM) and the AUA have announced the collaborative development of practice and training guidelines in the practice of urologic ultrasound, which has led to the availability of practice accreditation through the AIUM.