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For years, some urologists and physical therapists have been saying that the pelvic floor is contracted and shortened because of hypertonicity in patients with interstitial cystitis/painful bladder syndrome (IC/PBS), contributing to their misery. Now, using magnetic resonance imaging measurements, researchers have some physical confirmation that these patients do indeed have a contracted pelvic floor.

In just 18 patients, a multicenter phase Ib trial of an intravesical lidocaine-delivery device, called LiRIS (lidocaine-releasing intravesical system), not only knocked down pain and other symptoms for the 2 weeks the device was in the bladders of severely symptomatic patients, but in addition, the effects lasted 4 weeks and longer for many patients.