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Researchers teasing out the relationship between urinary tract infection and its symptoms are zeroing in on the major component of Escherichia coli's cell wall, lipopolysaccharide (LPS), as the culprit.

Phosphodiesterase type-5 inhibitors are safe and effective, alone or in combination with alpha-blockers, against lower urinary tract symptoms (LUTS) secondary to BPH, according to a systematic review and meta-analysis.

In phase II results presented here yesterday, the investigational beta3-adrenoceptor agonist solabegron yielded statistically significant improvements in symptoms of overactive bladder compared to placebo and was safe and well tolerated, Dutch researchers reported.

In the hands of high-volume surgeons, there is no evidence to suggest that robot-assisted laparoscopic prostatectomy (RALP) results in worse oncologic outcomes than open radical prostatectomy, even for patients with high-risk cancer, according to a retrospective study of patients operated on at a large tertiary care center.

Despite its well-established advantages over radical surgery, partial nephrectomy is not as likely to be used for older, sicker, and poorer patients who are uninsured or rely on Medicare or Medicaid for their health care, researchers from Henry Ford Hospital, Detroit reported here yesterday.

Juan A. Reyna, MD, who has served as president and CEO of Urology San Antonio for 16 years, has stepped down as the leader of the 29-physician group. He will continue to work as a urologist at the medical practice.

In a study identifying the risk of major birth defects associated with different types of assisted reproductive technology, Australian researchers have reported a significantly higher risk of birth defects involving intracytoplasmic sperm injection (ICSI) compared to in vitro fertilization (IVF).

About one-third of computed tomography scans performed following an inconclusive abdominal ultrasound examination have positive findings, according to a recent study. Follow-up scans appear to be most useful in the diagnosis of renal lesions.