Evaluating the Benefits of Cretostimogene Plus Pembrolizumab for BCG-Unresponsive NMIBC Management
Panelists discuss how the combination therapy of cretostimogene plus pembrolizumab offers a promising new approach for managing BCG-unresponsive non-muscle-invasive bladder cancer, highlighting its potential benefits and the implications of its FDA Breakthrough Therapy Designation for clinical practice.
EP: 1.Prevalence and Staging of Newly Diagnosed Bladder Cancer
EP: 2.Impact of BCG Therapy Shortage on the Management of High-Risk NMIBC
EP: 3.Recurrence and BCG Resistance in High-Risk NMIBC
EP: 4.Therapies Beyond BCG: FDA-Approved and Emerging Options
EP: 5.Cretostimogene, Grenadenorepvec, and Pembrolizumab for BCG-Unresponsive NMIBC: Overview of ASCO 2024 Data
EP: 6.CORE-001 Trial Participation and Eligibility Criteria
EP: 7.Comparing Cretostimogene and BCG Administration Methods
EP: 8.Results of the CORE-001 Trial: 24-Month Complete Response Rate and Duration of Response
EP: 9.Safety Outcomes and Duration of Response in Combination Therapy vs. Monotherapy for BCG UR CIS +/- Papillary Disease
EP: 10.Evaluating the Benefits of Cretostimogene Plus Pembrolizumab for BCG-Unresponsive NMIBC Management
EP: 11.Evaluating Cretostimogene: BOND-003 and PIVOT-006 Trial Results
EP: 12.Managing BCG-Unresponsive NMIBC: Cretostimogene Monotherapy vs. Combination Therapy
Video content above is prompted by the following questions:
- In your opinion, what does cretostimogene plus pembrolizumab combination therapy offer to the management of BCG-unresponsive NMIBC?
- Cretostimogene plus pembrolizumab received an FDA Breakthrough Therapy Designation in May 2023. What is important for physicians to know or understand about this designation?
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