December 3rd 2024
Data showed that all patients achieved a PSA decline of at least 50%.
November 25th 2024
Focal therapy: Magic bullet or unproven treatment?
April 23rd 2014Focal therapy has been promoted as a minimally morbid option for men with localized low-risk prostate cancer who nevertheless want their disease treated. Opponents of focal therapy note the heterogeneity and multifocal nature of prostate cancer, the difficulty of accurately targeting and destroying an index tumor with focal therapy, and the unknown biologic potential of the tumor.
Robotic vs. open RP: Equivocal results (again)
April 21st 2014A new study has found that for men 65 years of age and older, robot-assisted radical prostatectomy and open prostatectomy have similar rates of complications, providing further evidence that outcomes between the two procedures are not significantly different.
Advanced prostate cancer research focuses on newer agents for mCRPC
April 17th 2014Research in advanced prostate cancer is largely focused on newer agents for metastatic castration-resistant prostate cancer, including abiraterone acetate (ZYTIGA), enzalutamide (XTANDI), radium Ra 223 dichloride (Xofigo), and the immunotherapy sipuleucel-T (Provenge).
Urology Product Preview April 2014
April 16th 2014Drugs and devices in the pipeline from Astellas Pharma, Medivation, Repros Therapeutics, Metamark Genetics, Argos Therapeutics, S1 Biopharma, Ipsen, Sprout Pharmaceuticals, Antigen Express, Generex Biotechnology, Veloxis Pharmaceuticals, and Absorption Pharmaceuticals.
RT, hormonal combo treatment reduces prostate cancer mortality
April 10th 2014Adding local radiotherapy to hormonal treatment more than halves long-term prostate cancer-specific mortality and substantially decreases overall mortality in men with non-metastatic locally advanced or high-risk prostate cancer, according to an updated analysis of clinical trial data from the Scandinavian Prostate Cancer Group’s Study VII.
3-D mapping enhances accuracy of prostate biopsy
April 10th 2014Three-dimensional mapping biopsy (3DMB) of the prostate provides a more accurate disease assessment and in doing so may allow more confident decision making when patients and their physicians are trying to resolve issues surrounding observation or more aggressive therapies, a study from the University of Colorado School of Medicine, Denver, suggests.
Dose-escalated IMRT appears safe in prostate cancer patients
April 7th 2014Dose-escalated intensity-modulated radiation therapy (IMRT) with use of a moderate hypofractionation regimen (72 Gy in 2.4-Gy fractions) can safely treat patients with localized prostate cancer with limited grade 2 or 3 late toxicity, according to a recently published study.
AUA Exhibit Hall Highlights: Orlando 2014
April 2nd 2014This guide features products and services from manufacturers that are exhibiting at the AUA annual meeting in Orlando. Exhibit hall booth numbers have been included so that you can search for product demonstrations and exhibits that are of particular interest to you.
Post-abiraterone enzalutamide use viable in some men
March 21st 2014Although the activity of enzalutamide (XTANDI) is blunted in patients with metastatic castration-resistant prostate cancer who have been treated previously with abiraterone acetate (ZYTIGA), a meaningful number of these patients still experience a decline in PSA level with enzalutamide, according to a recent study.
No link found between testosterone replacement therapy, prostate cancer risk
March 21st 2014Testosterone replacement therapy (TRT) in hypogonadal men does not appear to increase the risk for prostate cancer, according to an evaluation of 224 men with an indication for prostate biopsy, providing further evidence that TRT need not be avoided in this patient group.
Higher surgeon volume linked to lower RALP costs
March 21st 2014A study from the UCLA Ronald Reagan Medical Center appears to once again prove that time is money. The study’s findings indicate that up to $15 million could be saved annually by referring patients who are candidates for robot-assisted radical prostatectomy to surgeons and surgical centers with optimal operating times.
Application for pre-chemo use of prostate cancer agent submitted
March 20th 2014Astellas Pharma Inc. and Medivation Inc. have submitted a supplemental new drug application to the FDA seeking approval of enzalutamide (XTANDI) capsules for the treatment of men with metastatic castration-resistant prostate cancer who have not received chemotherapy.
Drop in PSA screening greatest among urologists
March 17th 2014The U.S. Preventive Services Task Force recommendation against routine prostate cancer screening has resulted in a decrease in the number of PSA-based screenings ordered by physicians, with the greatest decline seen among urologists, according to findings of recently published study that one leading prostate cancer expert says raises more questions than it answers.
Studies target BPA, plasticizers in prostate cancer, fecundity
March 10th 2014Levels of bisphenol A in men’s urine could be a marker of prostate cancer, and male exposure to other environmental chemicals used in the manufacture of plastics appear to negatively impact time to pregnancy, two separate studies have found.
RP edges observation in young men with prostate cancer
March 6th 2014Radical prostatectomy is associated with a substantial long-term reduction in mortality in men with localized cancer, especially in younger patients, according to newly published data from one of the few randomized trials to directly address the surgery-versus-surveillance issue.
Study: Robotic RP yields fewer positive margins
March 3rd 2014Prostate cancer patients who undergo robot-assisted radical prostatectomy have fewer positive surgical margins and less need for additional cancer treatments such as hormone or radiation therapy than patients undergoing open surgery, an observational study from UCLA’s Jonsson Comprehensive Cancer Center has found.