
"There is clearly a lot of interest in the urologic oncology world toward bladder preservation for both muscle-invasive bladder cancer as well as early-stage non-muscle-invasive bladder cancer," says Arjun V. Balar, MD.

"There is clearly a lot of interest in the urologic oncology world toward bladder preservation for both muscle-invasive bladder cancer as well as early-stage non-muscle-invasive bladder cancer," says Arjun V. Balar, MD.

Brian T. Helfand, MD, PhD, NorthShore University HealthSystem, discusses the value of using multiparametric MRI and genomic testing together when making treatment decisions in prostate cancer.

Genetic counselor Samantha E. Greenberg, MS, MPH, CGC, on when to discuss genetic testing with prostate cancer patients.

Michael J. Morris, MD, discusses the rise of radiopharmaceuticals in prostate cancer and, in particular, the success of 177Lu-PSMA-617.

Wassim Abida, MD, PhD, discusses whether he would recommend PARP inhibitors in patients with metastatic castration-resistant prostate cancer harboring alterations in homologous recombination repair genes other than BRCA1/2.

“While many patients may think of imaging tests, as many other tests, as [having] a binary outcome, it may be important to have a discussion about how the scoring and MRI works, [and] what the patient can expect to see on their report,” says Stella K. Kang, MD.

An expert endourologist describes the prevalence and diagnostic processes of enteric hyperoxaluria, as well as common challenges faced in making a diagnosis.

Arjun V. Balar, MD, discusses notable findings from 2 separate studies of pembrolizumab (Keytruda).

“What I found exciting was that the extent to which a…PI-RADS 4 score saved biopsies without really affecting the likelihood of detecting clinically significant tumor,” says Stella K. Kang, MD.

Brian T. Helfand, MD, PhD, NorthShore University HealthSystem, discusses how genomic testing is a great tool for identifying “what is going on in the tumor ‘right now.’”

Arjun V. Balar, MD, describes the 2 “very distinct patient populations” of separate phase 2 studies from ASCO 2021 involving the treatment pembrolizumab (Keytruda).

Brian T. Helfand, MD, PhD, discusses how the precision of genomic testing data can alleviate the accuracy issues associated with PSA testing for screening and monitoring prostate cancer.

Brian T. Helfand, MD, PhD, NorthShore University HealthSystem, explains the increased significance of genomic testing in the field of prostate cancer.

Thomas Powles, MBBS, MRCP, MD, director, Barts Cancer Institute, discusses findings from the pivotal EV-301 trial of enfortumab vedotin.

"Same-day discharge is safe and feasible across a broad spectrum of FPMRS cases," says Jacqueline Zillioux, MD.

In this video, 5 urologists each weigh in on whether they listen to music in the OR, and if so, what they like to listen to.

Vinayak G. Wagaskar, MBBS, shares potential explanations for the obesity paradox in patients with metastatic castration-resistant prostate cancer and provides next steps for exploring this phenomenon.

Terrence Regan, MD, also discusses appropriate use criteria for advanced imaging from the Centers for Medicare & Medicaid Services.

This installment of Around the Practice focused on the multidisciplinary approach to bladder cancer care.

“There's a lot that urologists can pick up on how to better interact with their patients,” says David King Keller, PhD, of Active Surveillance Patients International.

Evangelia Sereti, MSc, PhD, discusses the design/methodology and results of a preclinical study exploring the combination of the PARP inhibitor olaparib plus the novel agent NOV202 in BRCA1/2-mutated prostate cancer cells.

“[Prior authorization is] becoming a bigger and bigger problem for each practice,” says urologist Terrence Regan, MD.

Vinayak G. Wagaskar, MBBS, explains the “obesity paradox”—improved survival outcomes in patients with a high body mass index—that has been observed in patients with genitourinary malignancies, including prostate cancer.

Bradley McGregor, MD, explains how despite the groundbreaking immunotherapy-based advances in metastatic renal cell carcinoma, unmet medical needs remain.

“[Prior authorization has] become part of our everyday practicing life, but it does very little to advance quality of care,” says Terrence Regan, MD.

“The key message from this abstract is that the time duration for starting avelumab [Bavencio] maintenance didn't really affect the outcomes,” says Shilpa Gupta, MD.

“The side that can take…complex issues and make them simple…is likely going to be the side that wins in a case,” says Kenton H. Steele, Esq.

Shilpa Gupta, MD, discusses several recent studies in the metastatic urothelial carcinoma space.

Urologists Steven M. Wahle, MD, and Henry Rosevear, MD, catch up with each other in this wide-ranging conversation.

Yousef Zakharia, MD, discusses the design and results of a phase 2 trial that explored concurrent treatment with radiation and the PD-L1 inhibitor durvalumab followed by adjuvant durvalumab in patients with urothelial cancer.