
Opinion|Videos|October 28, 2024
Exploring Emerging Data in NMIBC
Key Takeaways
- BladderGATE trial explores frontline use of PD1+BCG, showing promise in bladder cancer treatment advancements.
- Enfortamab vedotin and pembrolizumab combination is under investigation, potentially enhancing therapeutic efficacy.
Panelists discuss existing and upcoming data in non–muscle-invasive (NMIBC) bladder cancer treatment, including insights from the BladderGATE trial on frontline use of PD-1 inhibitors combined with BCG and the enfortamab vedotin plus pembrolizumab combination while also addressing the significance of clinical complete response as an end point and the potential role of circulating tumor DNA in future evaluations.
Advertisement
Episodes in this series

Video content above is prompted by the following:
- What other data exists? What upcoming data are you excited about? * (bladdergate, First Results of the Phase Ib-II BladderGATE exploring frontline use of PD1+BCG etc.)
- Enfortamab vedotin plus pembrolizumab combination
- Please discuss clinical complete response as an end point for these trials. What about circulating tumor DNA?
Advertisement
Related to this article

VOLGA results raise the question of treatment de-intensification in perioperative MIBC care, according to Suzanne B. Merrill, MD, FACS.

The combination of nogapendekin alfa inbakicept plus BCG demonstrated a statistically significant improvement in efficacy vs BCG alone.

These FAQs outline key recommendations from ASTRO's updated guideline on shorter-course radiation therapy for localized prostate cancer.

Patient goals, disease features, and response to prior therapy guide treatment choices across high-risk NMIBC, according to Suzanne B. Merrill, MD, FACS.

Suzanne B. Merrill, MD, discusses emerging perioperative approaches in MIBC and the potential for more personalized treatment selection based on disease characteristics.
Advertisement
Advertisement
Trending on Urology Times
1
FDA grants De Novo authorization to Virtuoso Robotic System for bladder tumor resection
2
Pasritamig combination yields 73% PSA response rate in phase 1 mCRPC study
3
FAQ: ASTRO guideline on hypofractionated radiation therapy for localized prostate cancer
4
Q&A: Suzanne B. Merrill, MD, FACS, on perioperative therapy in MIBC
5



