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NMIBC Treatment Insights: Standard of Care, BCG Immune Response, and Patient Outcomes

Panelists discuss how standard treatment options for non–muscle-invasive bladder cancer (NMIBC) include BCG therapy, exploring its mechanism of action in enhancing the immune response while also examining management strategies for intermediate and high-risk patients, optimal outcomes with single-agent BCG, and the discrepancies between observed rates of recurrence and progression in clinical practice and reported data.

Video content above is prompted by the following:

  1. What are the standard treatment options for non–muscle-invasive bladder cancer (NMIBC)? 
  • What are the management options for patients with intermediate and high-risk NMIBC?
  1. Can you explain the mechanism of action of BCG treatment in stimulating the immune response against bladder cancer?
  2. In an ideal treatment paradigm with single-agent BCG, what are the best outcomes for patients with high-risk NMIBC?
  • What are the rates of recurrence and progression?
  • What do you feel the rates of progression are in the real world vs what you see in your practice?
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