Opinion|Videos|January 7, 2025

Current Treatment Options for BCG-Unresponsive NMIBC

Author(s)Max Kates, MD

A panelist discusses how intravesical chemotherapy offers localized treatment with minimal systemic effects but requires frequent administration, while PD-L1 inhibitors show promising response rates yet come with immune-related adverse events, highlighting how each current treatment option presents distinct trade-offs among efficacy, safety, and convenience.

  1. Please review the standard treatment options (intravesical chemotherapy, PD-L1 inhibitors, other immunotherapeutic options) currently available for patients with BCG-unresponsive NMIBC.
    1. What advantages and limitations do these options have?

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