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Patients treated with pembrolizumab (Keytruda) as second-line therapy for advanced urothelial carcinoma following platinum-based chemotherapy maintain better health-related quality of life than their counterparts receiving chemotherapy, according to results from the phase III KEYNOTE-045 trial presented at the American Society of Clinical Oncology annual meeting in Chicago.

Despite technological advances in treatment for localized prostate cancer, men continue to experience clinically meaningful side effects that affect quality of life, according to an examination of data from a prospective population-based cohort study.

Metformin may act synergistically with androgen deprivation therapy to improve outcomes for men with advanced prostate cancer, according to findings of an observational study presented at the AUA annual meeting in Boston.

The proposed rule for MACRA and the Merit-based Incentive Payment System program was released June 21, 2017-- As expected, the program requiring the implementation of the new MIPS scoring system and incentives to move to alternative payment models will continue.

Quality improvement programs address all aspects of care and care delivery. Here are a few programs that impact urology, all of which were presented at the AUA annual meeting in Boston.

Changes in health care have made quality improvement (QI) program participation more than a good idea. Today, QI activities are part of the alphabet soup of regulations impacting provider pay.

Electroacupuncture involving the lumbosacral region is safe, well-tolerated, and can reduce the amount of urine leakage in women with stress urinary incontinence, researchers reported.

A quasi-randomized trial of open versus robotic radical prostatectomy and an evaluation of robotic inferior vena cava thrombectomy were among other key minimally invasive surgery studies at the AUA annual meeting in Boston.

An updated guideline on localized kidney cancer as well as a look at active surveillance as initial management for renal masses <2 cm were among the noteworthy kidney cancer studies at the AUA annual meeting in Boston.

A study documenting that male paternal age is increasing across the U.S. and a finding that men with Sertoli cell-only syndrome have increased damage to seminiferous tubules with aging are among the take-homes in infertility/andrology at the AUA annual meeting in Boston.

Other infection/inflammation take-home messages from the AUA annual meeting include a study of predictors of fluoroquinolone resistance in the rectal vault of men undergoing prostate biopsy and a study of 1,310 patients evaluated over 16 years for CP/CPPS.

A prospective evaluation of cancer detection rates with PI-RADS and the finding that use of micro-computed tomography enabled rapid phenotyping of GU anomalies in adult and embryonic mice were among other key imaging studies from the AUA annual meeting.