Videos

Panelists discuss how IsoPSA shows promise for equitable diagnostic performance but requires ongoing evaluation to ensure benefits reach all populations.

Panelists discuss how provider education and system-level support are vital for overcoming adoption barriers and ensuring IsoPSA is effectively used in practice.

This section explores how subcutaneous delivery can improve patient satisfaction, adherence, and quality of life through reduced treatment times and greater convenience.

Bertrand Tombal, MD, PhD, shares insights from the real-world REASSURE trial.

An expert discusses how the KEYNOTE-905 trial findings established pembrolizumab as a groundbreaking perioperative immunotherapy approach for cisplatin-ineligible muscle-invasive bladder cancer, significantly improving survival outcomes and redefining curative treatment strategies.

Petros Grivas, MD, PhD, touches on the signficance of KEYNOTE-905 data, which were presented at ESMO 2025.

Monique Roobol, PhD, MSc, noted that approximately half of the 30% higher incidence of prostate cancer in the screened arm represents overdiagnosis, primarily of low-risk cancers.

Aleece Fosnight, MSPAS, PA-C, encouraged urologists to normalize the conversation by openly acknowledging that these discussions can feel embarrassing but also by celebrating patients for taking the first step.

Freedland explores how enzalutamide’s role has expanded from advanced settings to earlier use in high-risk, biochemically recurrent prostate cancer. He discusses the clinical rationale for early initiation, particularly for urologists less familiar with systemic therapy, and compares enzalutamide with other androgen receptor pathway inhibitors in this population.

Rahul Aggarwal, MD, highlights final results from the phase 3 PRESTO trial in biochemically relapsed prostate cancer.

Qian Qin, MD, outlines the background and design of the phase 2 EXPLORE-RCC trial.

Petros Grivas, MD, PhD, highlights notable trial readouts across NMIBC, MIBC, and urothelial carcinoma.

Panelists discuss how understanding pharmacologic and mechanistic distinctions among androgen receptor pathway inhibitors helps clinicians tailor therapy selection and patient monitoring.

Panelists discuss how advances in systemic therapy have reshaped the treatment landscape for mCSPC, enabling more individualized and proactive first-line care.

Preliminary data from the study are promising.

The key finding was that men who received rectal spacers had a 50% lower risk of biochemical failure.

Panelists discuss how pairing IsoPSA with MRI strengthens risk assessment and supports more informed shared decision-making in prostate cancer care.

The segment reviews clinical trial outcomes and real-world findings on subcutaneous immunotherapy, focusing on efficacy, safety, and its practical application in daily urology practice.

Panelists discuss how IsoPSA strengthens diagnostic certainty by addressing gaps in MRI performance, offering a more reliable basis for biopsy decisions.

Pedro C. Barata, MD, MSc, FACP, outlines ARANOTE findings stratified by age subgroups.

Hear from 5 experts as they recap some of the top data from this year's ESMO Congress.

An expert discusses how he has integrated minimally invasive therapies into his practice workflow through a mutual evolution with his patients, noting that as these procedures became more amenable to office-based treatment, they lowered the bar for patient acceptance and allowed many who would have stayed on medications too long to undergo procedural intervention much earlier. The vast majority of his benign prostatic hyperplasia (BPH) work is now done in-office rather than in hospitals through advanced patient comfort techniques, including specialized lidocaine applications, bladder alkalinization with sodium bicarbonate, prostate nerve blocks, and nitrous oxide that allow about one-third of patients to fall asleep during procedures.

Panelists discuss how the promising approval of the gemcitabine intravesical system will likely drive future research into drug-device combinations for sustained drug delivery across various bladder cancer populations, including Bacillus Calmette-Guérin (BCG)-naive patients during shortages and muscle-invasive disease, potentially transforming localized bladder treatment approaches over the next decade.

Louise K. Kostos, MBBS, FRACP, PhD candidate, outlines initial findings from the phase 1/2 AlphaBet trial.

Beckermann explained that adenosine blockade may be better shown in the durability of response, so data collection in the study remains ongoing.

The findings revealed that patients prioritized improvements in overall survival and reductions in cancer recurrence at 5 years over all other treatment factors

Regarding the timing of sperm retrieval, the findings suggest it is reasonable and safe to delay the procedure until adulthood.

Chandler Park, MD, MSc, FACP, interviews urologist Neal D. Shore, MD, FACS, on the top updates in prostate cancer and bladder cancer at the 2025 European Society for Medical Oncology Congress.

Regarding feasibility, Helo highlighted that the asynchronous format is resource-efficient.